HFRSLast updated 2025-12-01
Hantavirus in China
China has historically accounted for a majority of global HFRS cases. National vaccination campaigns using a bivalent Hantaan/Seoul vaccine have significantly reduced incidence over the past two decades.
Cumulative Cases
45,000
Deaths
1,200
CFR
2.7%
Global Rank
#1
by case count
Circulating Strains
- ●Hantaan virus (HTNV)
- ●Seoul virus (SEOV)
Primary syndrome: Hemorrhagic Fever with Renal Syndrome (HFRS).
Reservoir Species
- • Striped field mouse (Apodemus agrarius)
- • Brown rat (Rattus norvegicus)
Most Affected Regions
- • Shaanxi
- • Heilongjiang
- • Shandong
- • Liaoning
Country-specific Risk & Prevention
Vaccination is offered to high-risk rural populations. Grain warehouses and rodent-infested farmland present the greatest exposure risk.
General prevention: see symptoms and prevention guidance →
Field Notes
Hantaan and Seoul viruses. Primarily in rural agricultural regions.