HPSLast updated 2025-11-15

Hantavirus in Argentina

Argentina is one of the highest-burden HPS countries globally. Andes virus, endemic to Patagonia, is the only hantavirus with documented person-to-person transmission. The 1996 Bariloche cluster and the 2018–2019 Epuyén outbreak are landmark events in hantavirus epidemiology.

Cumulative Cases

1,200

Deaths

380

CFR

31.7%

Global Rank

#8

by case count

Circulating Strains

  • Andes virus (ANDV)
  • Laguna Negra virus

Primary syndrome: Hantavirus Pulmonary Syndrome (HPS).

Reservoir Species

  • Long-tailed pygmy rice rat (Oligoryzomys longicaudatus)

Most Affected Regions

  • Patagonia (Río Negro, Chubut, Neuquén)
  • Salta
  • Buenos Aires province

Country-specific Risk & Prevention

The MV Hondius cruise-ship outbreak of 2026 is suspected to trace back to a landfill site near Ushuaia. Travelers should avoid contact with rodents and droppings in southern Argentina, particularly during summer-tourism months.

General prevention: see symptoms and prevention guidance →

Field Notes

Andes virus. Person-to-person transmission documented. Patagonia region most affected.

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