Last reviewed 2026-05-14

What hantavirus strains exist and which rodents carry them?

Short answer

The medically important hantaviruses include Sin Nombre virus (deer mouse, North America), Andes virus (long-tailed pygmy rice rat, southern South America), Hantaan virus (striped field mouse, East Asia), Puumala virus (bank vole, Europe), Seoul virus (brown rat, worldwide), Dobrava-Belgrade virus (yellow-necked mouse, the Balkans), and several regional New World strains including Choclo (Panama), Juquitiba and Araraquara (Brazil), and Laguna Negra (Paraguay).

Hantaviruses are reservoir-host specific: each virus is maintained in one or a few rodent species, and human infection occurs as a spillover. Sin Nombre virus is the dominant New World hantavirus in North America and is carried by the deer mouse (Peromyscus maniculatus); it causes HPS. Andes virus, carried by the long-tailed pygmy rice rat (Oligoryzomys longicaudatus), causes severe HPS in Argentina and Chile and is uniquely capable of person-to-person spread. Hantaan virus, carried by the striped field mouse (Apodemus agrarius), causes the most severe HFRS in East Asia. Puumala virus, carried by the bank vole (Myodes glareolus), causes the milder nephropathia epidemica syndrome across northern Europe. Seoul virus, carried by Norway rats (Rattus norvegicus), has a worldwide distribution wherever Norway rats are established and causes moderate HFRS. Other significant strains include Dobrava-Belgrade virus in the Balkans, and Juquitiba, Araraquara, Castelo dos Sonhos, and Laguna Negra viruses in Brazil, Paraguay, and the broader Southern Cone.

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HantaWatch. "What hantavirus strains exist and which rodents carry them?." Reviewed May 14, 2026. https://www.hantawatch.app/facts/hantavirus-strains-and-reservoirs